Most cases of aTTP occur in adults, but the disease can also affect children.

Acquired means youre not born with the condition.

Purpura describes purple bruises due to bleeding under the skin.

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But they have identified risk factors that make this process more likely, including several health conditions.

How Is aTTP Diagnosed?

During that time, you may experience severe complications and damage to your organs, including brain damage.

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The condition may also be fatal.

Without any treatment, aTTP has a 90 percent mortality rate, according to the Cleveland Clinic.

But with prompt and appropriate treatment, the mortality rate is between 10 and 20 percent.

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People who develop aTTP once are more likely to develop the condition again.

It is used in combination with plasma exchange and other drug treatments.

Thats because your spleen creates the antibodies that attack the ADAMTS13 enzyme in aTTP.

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Your spleen is an organ located in the upper left area of your abdomen.

Splenectomy is recommended as a treatment for aTTP only when other treatments are unsuccessful in stopping the disease process.

Getting prompt treatment for aTTP is essential to reduce your risk of serious complications due to the condition.

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Research and Statistics: Who Has aTTP?

There is limited data on how common aTTP is in the United States.

Two-thirds of people with aTTP are women, according to NORD.

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The a in aTTP stands for acquired, meaning youre not born with the condition.

There is also a form of TTP that is genetic and is due to mutations in the ADAMTS13 gene.

But inherited TTP may also not cause any problems until adulthood, such as during a first pregnancy.

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She is married with two adult daughters, a dog, and two cats.

She enjoys hiking and playing classical and jazz piano.

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