It’s also known as S-adenosyl methionine and S-adenosylmethionine.
Like with many nutritional supplements, your body naturally produces SAMe and uses it to regulate cell function.
Abnormal levels of SAMe have been observed in people with medical conditions like liver disease and depression.
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Some research indicates suggests that the supplement may help alleviate symptoms of these conditions.
However, more evidence is needed to better understand its effects.
Depression
The effectiveness of SAMe for alleviatingdepression symptomsin people with the condition has been inconclusive.
SAMe also seems most effective when administered as an injection instead of orally for depression.
If you have Alzheimer’s disease, you should not take SAMe before talking to your doctor.
Liver Diseases
Research shows that SAMe could benefit people living with different forms of liver diseases.
According to scientists, the supplement may increase liver function in people with chronic liver diseases like cirrhosis.
NSAIDs are known to cause troubling side effects such as stomach ulcers, headaches, drowsiness, and dizziness.
More research is needed to determine if SAMe might be an alternative to NSAIDs.
Talk to your doctor about your pain relief options to determine what is right for you.
Possible Side Effects of SAMe
Taking SAME supplements can cause side effects in certain people.
SAMe is contraindicated with the use of specific supplements and medications.
In people with Parkinson’s.
Dosage and Preparation
Unlike many dietary supplements, SAMe can’t be derived from any food source.
The only way to address a SAMe deficiency or imbalance is by taking supplements.
Supplements are available in tablet and capsule forms, which helps you regulate your dosage.
Some experts advise buying the supplement in blister packs instead of bottles for this reason.
Start with a low dosage to avoid side effects is often recommended.
Speak with your healthcare provider to determine the appropriate dosing of SAMe for you.
There have been conflicting suggestions on the proper dosage of SAMe for different conditions.
SAMe has been shown to contraindicate with certain medications and worsen symptoms in people with conditions likebipolar disorder.
You shouldn’t stop taking the medication for any condition that has proven beneficial when SAMe is used.
Clear any supplements and dosages with your doctor before you get going.
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