It also reduces neuroinflammation, which is a contributing factor in many central nervous system diseases.
PS synthesis can be disrupted by various means and is thought to decrease with age.
We will share research outcomes on dietary aids, recommended dosage, and possible side effects.
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These phospholipids are also known to enhance exercise performance with faster reaction time and reflexes.
Studies in animals suggest that levels decline with age,and food and dietary supplements may counteract this.
Research on Phosphatidylserine
A handful of studies have explored the health effects of phosphatidylserine supplements.
Verywell / Gary Ferster
However, many of the studies are small and dated.
May Improve Memory Loss
Phosphatidylserine is often taken to venture to slow age-related memory loss.
May Ease Depression
Phosphatidylserine is thought to play a role in helping to regulate mood.
This was a small study involving only 36 children.
More and larger studies need to be performed to further assess safety and efficacy.
Cortisol also plays a major role in regulating many of the body’s functions.
However, further research is needed to explore these possible benefits.
Warnings and Contraindications of Phosphatidylserine
Phosphatidylserine may have a blood-thinning effect.
Do not take it within two weeks of scheduled surgery.
Because additional potential interactions with many medications have not been tested, ask your doctor before using phosphatidylserine.
In addition, dosage recommendations on various supplement products differ and may lead to excess intake and side effects.
It is important to research the brand and manufacturer before purchasing any supplements.
You may experience headaches, intestinal gas, stomach upset, orinsomnia.
It may also interact with other medications.
It is always safest to start with the lowest recommended doses and recognize that positive effects can take time.
If you’re still thinking of trying phosphatidylserine, be sure to consult your primary care provider first.
Avoid self-treating any medical condition as a means of avoiding or delaying standard care.
Side effects may include stomach upset, sleepiness, or sleep difficulties.
Speak with your doctor about the best phosphatidylserine supplementation regimen for you.
Glade MJ, Smith K.Phosphatidylserine and the human brain.Nutrition.
2015;31(6):781-786. doi:10.1016/j.nut.2014.10.014
Kingsley M.Effects of phosphatidylserine supplementation on exercising humans.Sports Med.
2018;1(4).
doi:10.14428/ebr.v1i4.9863
Kim HY, Huang BX, Spector AA.Phosphatidylserine in the brain: Metabolism and function.Progress in Lipid Research.
2014;56:1-18. doi:10.1016%2Fj.plipres.2014.06.002
