It works by moderating extreme variations in mood and is particularly helpful in treating severe depression.
Since its introduction in 1994, the medication has enjoyed widespread use.
Today, it is on the World Health Organization’s List of Essential Medications.
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Despite its proven benefits, Lamictal has its downsides.
In some individuals, Lamictal has been known to cause a hypersensitivity reaction marked by severe rash and inflammation.
If you experience a rash while taking Lamictal, see your doctor immediately.
If it is spreading quickly, call 911 or go to your nearest emergency room.
It is far better to be safe than sorry, no matter how low the risk may be.
The symptoms can range from benign to potentially fatal.
However, there is no way to gauge the potential outcome based on the symptoms.
Mortality rates are significant, ranging from 5% to as high as 30%.
Toxic Epidermal Necrolysis
Toxic epidermal necrolysis (TEN) is essentially SJS but worse.
If you are under 16, the risk will further double.
It is important to note, however, that not all hypersensitivity reactions will result in SJS.
Putting it all into perspective, there is only a 0.1% chance of such an event occurring.
The skin damage is treated in a similar manner to a thermal burn.
Corticosteroids are commonly used to reduce inflammation.
Research also suggests that Zyprexa (olanzapine) can help manage symptoms of bipolar disorder.
People may also notice itching, hives, or a general feeling of unwellness.
World Health Organization.WHO model lists of essential medications.
GlaxoSmithKline.Lamictal (lamotrigine): Highlights of prescribing information.
2014;14:145. doi:10.1186/1471-244X-14-145
Aiken C.How to minimize lamotrigines adverse effects.Psychiatric Times; 2018.
2018;43(3):48-51. doi:10.1097/01.NPR.0000530211.32278.96
