Medications for panic disorder are typically from one of two categories: antidepressants and anti-anxiety drugs.
This article discusses how medications are used to treat panic disorder and which medications are most often prescribed.
It also covers some of the other treatment options that may be effective for panic symptoms.
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Panic Disorder Treatment
Treatment for panic disorder may involve medication in addition to psychotherapy.
In some cases, more than one medication may be prescribed to help manage symptoms of panic and anxiety.
Psychotherapy can also be effectivein treating panic disorder.
Antidepressant medications are now commonly used to treat many anxiety disorders, including panic disorder and agoraphobia.
Antidepressants affect the chemical messengers in the brain,known as neurotransmitters.
There are thought to be many different types of these chemical messengers that communicate between brain cells.
Norepinephrine is a neurotransmitter that plays a role in concentration and alertness.
However, TCAs can still be an effective treatment option for people withanxiety disorders.
Like SSRIs, TCAs work to block the reuptake of the chemical messenger serotonin.
MAOIs work by inhibiting the activity of the enzyme monoamine oxidase.
This enzyme is involved in breaking down neurotransmitters like norepinephrine, serotonin, and dopamine.
Dopamine helps regulate many functions, including movement, physical energy levels, and feelings of motivation.
Anti-Anxiety Medications
Anti-anxiety medications are prescribed for their fast-acting relief of panic symptoms.
Due to their tranquilizing effect and rapid relief, anti-anxiety medications are often prescribed to treat panic disorder.
Benzodiazepines
Benzodiazepines are the most commonly prescribed class of anti-anxiety medication for panic disorder.
While effective, benzodiazepines can produce physical dependence.
You should not stop taking benzodiazepines without talking to your doctor first.
Benzodiazepine withdrawal can be dangerous.
It is important to gradually reduce your dose under the supervision of your doctor to avoid potential withdrawal complications.
For more mental health resources, see ourNational Helpline Database.
The best way to ask is to be direct.
Tell your doctor that you are experiencing panic attacks and need medication to help manage these symptoms.
Non-habit-forming medications that can help with panic attacks and anxiety include SSRIs, SNRIs, and beta-blockers.
Others that may be helpful includeBusparandVistaril.
Benzodiazepines are fast-acting and work to relieve anxiety symptoms right away.
This is why they are a good option for short-term relief of panic attacks.
2016;10(10):CD011170.
2020;11:595584. doi:10.3389/fpsyt.2020.595584
Bandelow B, Michaelis S, Wedekind D.Treatment of anxiety disorders.Dialogues Clin Neurosci.
2017;19(2):93-107.
Carhart-Harris RL, Nutt DJ.Serotonin and brain function: A tale of two receptors.J Psychopharmacol.
2019;36(3):198-212. doi:10.1002/da.22854
Food and Drug Administration.Highlights of prescribing information: Effexor XR.
Schneider J, Patterson M, Jimenez XF.Beyond depression: Other uses for tricyclic antidepressants.CCJM.
2013;15(5):PCC.13r01515.
2013;13(2):214-223.
Balon R, Starcevic V.Role of benzodiazepines in anxiety disorders.Adv Exp Med Biol.
2017;8:874. doi:10.3389/fpsyg.2017.00874
American Psychiatric AssociationDiagnostic and Statistical Manual of Mental Disorders, 5th ed.
Preston JD, O’Neal JH, Talaga MC.Handbook of Clinical Psychopharmacology for Therapists, 6th ed.
Silverman HM.The Pill Book, 15th ed.