How to Spot the Signs of Antidepressant Overdose

Yes, it is possible to overdose on prescription antidepressants.

When used properly antidepressants can be an effective means of treating depression, anxiety, and other mood disorders.

However, they can have also seriousside effectsand be dangerous if taken incorrectly or used with alcohol or drugs.

signs of an antidepressant overdose

Verywell / JR Bee

Some people may misuse or overdose on antidepressantsintentionally or notto increase the drugs' effects or becausethey are suicidal.

The first signs of antidepressant overdose are usually symptoms that can all be attributed to other causes.

This symptom warrants a call to 911 or an immediate visit to the emergency room.

If you experience any side effects, contact a doctor immediatelyeven if the side effects feel mild.

You may want to talk to a doctor even if you don’t experience any effects.

They can offer reassurance and teach you to monitor yourself for possible side effects.

Treatment

Emergency medical interventions are often needed for serious antidepressant overdoses.

Intravenous sodium bicarbonate and other medications may also be prescribed to counteract the effects of the drug.

The person will be kept hydrated with intravenous fluids.

If there are breathing difficulties, the person may need mechanical ventilation.

The heart will be monitored and treatment will be provided for any cardiac problems.

If the person experiences seizures, drugs will be given to control them.

The FDA requires that all antidepressants carryblack box warnings, which are the strictest warnings for prescriptions.

Some antidepressants are also linked to episodes ofmaniaorhypomaniain people with a history of these conditions.

(Mania and hypomania are characteristic ofbipolar Iand bipolar II, respectively).

This was especially true for the TCA drugs Prothiaden (dosulepin) and Silenor (doxepin).

Of the SSRIs, Celexa (citalopram) had the highest toxicity and fatality rate.

You should never stop taking antidepressants suddenly; always talk with your doctor before making changes to your medication.

Your doctor will advise you how best to discontinue your medication and whether you shouldstop your antidepressant gradually.

If you are having suicidal thoughts, contact theNational Suicide Prevention Lifelineat988for support and assistance from a trained counselor.

If you or a loved one are in immediate danger, call 911.

For more mental health resources, see ourNational Helpline Database.

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